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    Try out PMC Labs and tell us what you think. Learn More. Objective measurements are required for computer-aided sperm morphometric analysis CASMA machines to distinguish normal from abnormal sperm heads. For each man a homogeneous population of distributions characterized seminal spermatozoa 7 cells: median values L 4. Different men could have spermatozoa of significantly different dimensions. Although these samples were not biologically matched, linear mixed-effects statistical analyses permitted valid comparison of the groups.
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    Macrozoospermia: MedlinePlus Genetics

    Sperm morphology refers to the shape of the sperm, which includes head size and head DNA content revealed by a nuclear color stain , the midpiece appearance and the structure of the tail. Sperm morphology is assessed during routine semen analysis that examines the sperm cells under a microscope. The semen analysis will also examine the motility movement ability and concentration of sperm present. Every male, fertile or infertile, has varying percentages of abnormally-shaped sperm. There are many factors that can lead to abnormally shaped sperm including increased testicular temperature, exposure to toxic chemicals, infection and genetic traits. The medical term for when a man has a large number of abnormally shaped sperm is teratozoospermia or teratospermia.
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    Sperm Morphology (Size and Shape)

    Devillard, C. Metzler-Guillemain, R. Pelletier, C.
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    Macrozoospermia is a condition that affects only males. It is characterized by abnormal sperm and leads to an inability to father biological children infertility. In affected males, almost all sperm cells have abnormally large and misshapen heads. The head of the sperm cell contains the male's genetic information that is to be passed on to the next generation.
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